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This activation leads to downstream suppression of inflammatory mediators while promoting anti-inflammatory cytokine release

Differential diagnosis Low levels of GSH can also be due to glutathione synthetase deficiency

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The inhibition of NF-B (nuclear factor kappa-light chain enhancer of activated cells) binding was associated with reduction in the expression of 2 key proinflammatory cytokines, TNF (tumor necrosis factor alpha) and IL-1 (interleukin1 )