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These cells originate in the bone marrow, circulate systemically, and conduct immune surveillance
Finally, 150 L of scintillation cocktail (OptiPhase SuperMix, PerkinElmer) was employed and radioactivity (counts per minute, CPM) determined by a scintillation counter (MicroBeta2 plate counter, PerkinElmer)
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It can be found naturally in the body and was discovered in the early 20th century
Elevated levels of ferritin and transferrin, markers of iron dysregulation, have been observed in clinical ARDS cases, linking iron metabolism to disease severity ( Mitochondrial dysfunction exacerbates iron-driven ferroptosis by impairing the organelles ability to sequester and regulate iron levels
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