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Introduction Chronic pain and depression are leading causes of disability that are frequently encountered comorbidly in a variety of clinical conditions, sharing genetic and psychological risk factors, a relapsing-chronic course, and neurobiological features ( Because of global aging, the prevalence of pain, depression, and comorbid pain and depression is expected to increase ( We assessed the effects of two clinical glutamate modulators, acetyl-L-carnitine (ALCAR) and ketamine (KET), on regional glucose cerebral metabolism and on patients with comorbid pain and depression

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ScienceDirect Salehpour S, Nazari L, Hoseini S, Moghaddam PB, Gachkar L

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Safety is uncertain due to: lack of long-term data inconsistent dosing unregulated products which peptide you are referring to there are a lot of different types

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