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Considering that this amino acid is essential for central nervous system (CNS) function and development ( We found a significant decline in plasma sarcosine levels in LC patients, which is also reported in critically ill COVID-19 patients ( Despite previous reports on the role of tryptophan/serotonin in anxiety and depression ( The lower arginine in LC patients as reported in acute COVID-19 (58, 59) or the pathology associated with the effects of the virus on the endothelium (60)

Anxiety is highly treatable, and the National Institute of Mental Health emphasizes that effective treatment options exist for people living with anxiety

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First treatment has partially diminished the sharp pain while in full extension