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According to Yucca Health's safety information pages, the most common side effects include: Gastrointestinal Effects: Nausea (most common, especially early on) Diarrhea Constipation Vomiting Indigestion and abdominal discomfort Feeling full quickly after eating Other Common Effects: Headache Fatigue Dizziness Managing Side Effects: Most patients find that nausea and gastrointestinal symptoms improve as the body adjusts to the medication

The simplest way to think about it: Wegovy and Zepbound work by targeting specific receptors in your bodyWegovy focuses on GLP-1, while Zepbound activates both GLP-1 and GIP receptors