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Ludvik B, Giorgino F, Jdar E et al (2021) Once-weekly tirzepatide versus once-daily insulin degludec as add-on to metformin with or without SGLT2 inhibitors in patients with type 2 diabetes (SURPASS-3): a randomised, open-label, parallel-group, phase 3 trial

Additional information The original online version of this article was revised to include a sentence and a reference

Compound CJC-1295 (No DAC) + Ipamorelin blend Contents CJC-1295 (No DAC) 5mg + Ipamorelin 5mg (10mg total) CJC-1295 (No DAC) Modified GRF (1-29), MW ~3367.9 g/mol Ipamorelin CAS 170851-70-4, MW ~711.9 g/mol Purity 99% (HPLC verified) Form Lyophilised powder blend Packaging Sealed sterile research vial Storage (lyophilised) 28C, avoid repeated freeze-thaw Storage (reconstituted) 28C, use within 28 days Reconstitution Bacteriostatic water (recommended)

Their pharmacological actions include: (i) weight reduction, achieved by modulating and neuronal activity in the arcuate nucleus and lateral hypothalamus to reduce hunger and rewards-driven eating

For owners, this does not translate into self-treatment

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