Hepatic glutathione concentrations typically range from 5 to 10 mmol/L [5]
By maintaining high levels of GSH, cardiovascular tissues can effectively counteract oxidative stress, safeguarding the integrity of cellular components, including lipids, proteins, and DNA
Yes, short-term supplementing with 2000 mg of vitamin C and 1400 IUs of vitamin E (those are some high doses!) lowers muscle damage and inflammatory responses
The local expression and abundance of insulin-like growth factor (IGF) binding proteins in skeletal muscle are regulated by age and gender but not local IGF-I in vivo. 2005 Anderson, J., et al
Furthermore, the GSH-dependent antioxidant enzymes (glutathione peroxidase-1, glutathione reductase, glutathione S-transferase) cooperate and are interconnected reactions that eliminate ROS or controlled the redox state
PLoS ONE 17 , e0264696 (2022)