The timing principle applies across the stack
They may provide significant cardiovascular benefits, as many RA and PsA patients are at increased risk for heart disease
They do not add volume, tighten tissue, or resurface skin in the way a device-based treatment might
Only medullary thyroid carcinoma and MEN2 syndrome prevent GLP-1 use
Emerging therapies, such as Tirzepatide, a dual GLP-1/GIP agonist, and Orforglipron, a nonpeptide oral GLP-1 RA, continue to expand the potential of this medication class in treating metabolic diseases (23)(24)
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