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Proc Intl Soc Magn Reson Med 18:3324 Cudalbu C, Mlynrik V, Gruetter R (2012a) Handling macromolecule signals in the quantification of the neurochemical profile

Here, we used PURE G4 partially functionalized with lactate molecules (LA) at the surface, a conjugation strategy to direct these nanoparticles to MCT1 expression related to increased glycolysis and complexed with anti- GLS1 small interference RNAs (anti- GLS1 -siRNAs) to target glutamine metabolism in GBM cells

doi: 10.3945/an.115.008623