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Curcumin induces apoptosis and cell cycle arrest via the activation of reactive oxygen speciesindependent mitochondrial apoptotic pathway in Smad4 and p53 mutated Colon adenocarcinoma HT29 cells
No, peptide therapy is typically done in cycles rather than continuously
A clinical convenience
Acknowledgements The authors thank the research resource division (RRD) (RIKEN Center for Brain Science) and RIKEN CBS-EVIDENT Open Collaboration Center (RIKEN Center for Brain Science) for technical assistance, Yukiko Nagai (RIKEN Center for Brain Science) for secretarial work, Kenichi Nagata (Nagoya University) and members of the Laboratory for Proteolytic Neuroscience (RIKEN Center for Brain Science) for beneficial suggestions
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Mutations in the CBS gene can cause disorders like Downs syndrome and peripheral neuropathy
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