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J Colloid Interface Sci 689:137207 Chen LJ, Liu YY, Zhao X, Yan XP (2022) Vancomycinfunctionalized porphyrinic metalorganic framework PCN224 with enhanced antibacterial activity against Staphylococcus Aureus

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Each freeze-thaw cycle stresses the peptide in solution and can cause aggregation, the process by which peptide molecules clump together and lose biological activity

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