The fate of taspoglutide, a weekly GLP-1 receptor agonist, versus twice-daily exenatide for type 2 diabetes
Tolerability screening The lower systemic exposure from nasal delivery could serve as a tolerability screen before full-dose subcutaneous injection
This is why you can experience both mild and severe side effects
For alcohol, slowed stomach emptying can change the timing of how it hits you
China approves Eli Lilly's blockbuster diabetes drug Tirzepatide, which also has weight-loss effects and is direct competition for Novo Nordisks semaglutide, is also under review in the country as an obesity treatment
Regardless of timing, the following general measures may help manage side effects: Eat smaller, more frequent meals rather than large portions Avoid high-fat or spicy foods around the time of injection Stay well hydrated to reduce nausea and support kidney function When to seek urgent medical attention: Contact your GP, trial team, or NHS 111 promptly if you experience severe or persistent abdominal pain (particularly if it radiates to the back), vomiting that prevents you from keeping fluids down, signs of jaundice (yellowing of the skin or eyes), fever, or significantly reduced urine output