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The 48-68 hour steady-state half-life comfortably supports once-daily dosing with relatively stable plasma concentrations throughout the dosing interval

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Due to MTII's broad, non-selective receptor activity, researchers and regulatory agencies have raised concerns about potential effects on melanocytic nevi (moles) and theoretical melanoma risk through excessive MC1R stimulation

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Altered poop color Those with constipation or diarrhea may notice different colored poop