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Also, they stimulate the endothelium to produce nitric oxide, reduce oxidative stress, and have antiatherogenic and anti-inflammatory effects

For this study, any SUD was operationalized as the presence of at least one diagnosis of AUD, OUD, NUD, or CUD

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Quantitative data between groups were compared by one-way ANOVA if normally distributed or KruskalWallis H-test if not

As such, the availability of NADPH plays a central role in maintaining the intracellular GSH/GSSG ratio and overall redox buffering capacity