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Mild fatigue or lightheadedness during the first weeks of MOTS-c (AMPK adaptation)

Acute fractures benefit from early peptide intervention (within days of injury) supporting rapid callus formation and preventing non-union complications

Laboratory Safety Protocols General chemical safety practices should be followed when handling AOD 9604

Ensure adequate sleep (79 hours) to optimize recovery and tissue regeneration

This disparity underscores a critical knowledge gap that must be resolved before confident, evidence-based clinical adoption can be justified

Test stage: On day 6, the platform was removed and the mice were placed in the quadrant farthest from the platform