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Clinical evidence for oral semaglutide versus placebo and other oral antihyperglycemic agents 2.1
CagriSema's side effects were mostly mild to moderate gastrointestinal complaints, so the miss was about efficacy rather than tolerability
42 2021 Hendershot, Christian S, et al
As a member, your provider can help recommend the right support pack based on your lab results, goals, and medication planso you get even more from your program
Regular exercise: Incorporate physical activity into your daily routine
Plain water is inadequate for ESD: insufficient conductivity higher diathermy settings required Isotonic saline (0.9% NaCl): electrolyte-rich conductive medium facilitates cutting, coagulation and vessel precoagulation ESGE 2023 guidelines explicitly endorse saline over water in immersion-assisted ESD SITE-PCM: especially powerful combination the pocket stabilises the dissection plane, SITE optimises optics, buoyancy and diathermy performance Asclepius tube: continuous drainage of excess saline without repeated through-the-scope suctioning Western cohort data (181 lesions, Royal Free): R0 92.3%, curative resection 90.6%, 93.4% under conscious sedation, 0.5% surgery rate Conclusion: SITE is not a competitor to conventional ESD it is a flexible adjunct, most valuable in fibrotic lesions, anatomically challenging segments, and for broadening access to ESD without general anaesthesia
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