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Diabetologia 64, 142151
In ARPE-19 cells, we found that, compared to SG, HG significantly increased the mRNA expression of these genes 24 h after exposure (Fig
FOXO4-DRI, designed to disrupt the FOXO4-p53 interaction, was tested on senescent TM3 Leydig cells
That is clinically meaningful for a specific subset of patients
This selectivity allows for neuroprotection and tissue repair without the thrombotic risks of EPO
Improves the function of vital organs FOXO4-DRI holds significant potential in improving organ function, including the kidneys, by targeting harmful senescent cells
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