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Animal-model evidence consistently shows local effects: angiogenesis at the injury site (VEGF upregulation), growth-factor signaling (EGF, FGF), nitric oxide pathway modulation, and accelerated tendon-to-bone interface healing in rat Achilles transection studies

They also looked at melittins anti-inflammatory properties through its associations with IKKs

The thickness of the blue arrows represents the concentration of xenobiotics

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Ng and colleagues (2000) demonstrated that the fragment stimulated lipolysis in isolated rat adipocytes with potency comparable to full-length hGH, while failing to elicit growth-promoting or glucose-disrupting effects