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For people who suffer from anxiety or depression, low serotonin levels tend to worsen symptoms [6]

A critical analysis of the clinical use of incretin-based therapies: The benefits by far outweigh the potential risks

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These microbial shifts trigger cascading gutbrain disruption by impairing neurotransmitter signaling, suppressing SCFA production, weakening epithelial barrier integrity, and activating neuroimmune pathways, ultimately resulting in anxiety- and depression-like behaviors in rodent models (Tejkalov et al., 2023

While tirzepatide has a more potent effect on blood sugar control and weight loss, it also has a higher incidence of gastrointestinal side effects and hypoglycemia

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