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This process, known as osteoarthritis, can lead to: persistent stiffness pain during walking reduced mobility swelling after activity difficulty climbing stairs progressive loss of joint function Although osteoarthritis is often associated with aging, previous injuries, excess body weight, genetics, and occupational demands can all contribute to its development

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The results suggest that PCs augment high glucose-induced apoptosis in pancreatic -cells by increasing glucose uptake under high glucose conditions, potentially via a mechanism that downregulates Gck and promotes Bax protein translocation and oligomerization at the mitochondrial membrane