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This applies to topical treatments such as niacinamide

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Micronutrient approaches to treatment of diabetic complications People with diabetes have reduced antioxidant capacity which lays the basis for usage of antioxidant vitamins such as carotene or vitamin C or E

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4.2 Perinatal factors 4.2.1 Birth by caesarean section Birth by caesarean section (CS) is associated with adverse immune effects including predisposition to infections, allergies, and inflammatory disorders, probably related to failure to collect the vaginal microbiota