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Molecular modeling indicates that the substitution of a valine to glutamic acid at residue 411 reduces the binding affinity of linolenic acid, a reported exogenous ligand for the NHR-49 ortholog, HNF4, as well as other potential fatty acid binding partners with comparable structure (Supplementary Fig
Helicobacter 20, 206216 (2015)
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Bibcode:2003PNAS..100.9785L
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