Discussion We previously demonstrated that elevating Rab7-GTP levels upon Rab7-GAP TBC1D15 gene depletion enabled activation of cholesterol export routes from LE/Lys, reducing cholesterol accumulation in NPC1 mutant cells [12]
A large real-world study published in 2026 in the journal Inflammatory Bowel Diseases found that GLP-1 use in people with UC and Crohns disease was linked to lower rates of steroid use, hospitalization, and intestinal surgery
Intestinal microbiota, diet and health
Spencer JP, Thomas S, Trondsen Pawlowski RH
Singer , Senior Fellow, Cato Institute Tracy Zvenyach , Director, Policy Strategy & Alliances, Obesity Action Coalition 3:50 | Audience Q&A 4:25 | Closing Remarks 4:30 | Adjourn Health in the Headlines This event is part of the National Academy of Medicines Health in the Headlines series, which investigates high-profile health and health policy topics making the news
MOTS-c is the peptide most directly tied to mitochondrial function, since it is encoded in mitochondrial DNA and signals mitochondrial stress [2][3]