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194 Despite these potential genetic correlates, variants account for only 25% to 44% of the heritability of IR
Importantly, the study showed that 32.3% of participants in the combined intervention group achieved clinically significant weight loss of 5% or more, compared to 20.8% in the online program only group
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They also benefit those with specific medical conditions, such as chronic fatigue or difficulty losing weight
Galstyan, G., Karataeva, E., & Yudovich, E
![PDF] Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 2·4 mg for weight management: a randomised, controlled, phase 1b trial](https://figures.semanticscholar.org/e338e8f8bf819030be1ae81167c7d20946acbbb5/9-Figure3-1.png)
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