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10.1016/j.cub.2008.12.005 43 ShinJ
Oxidative stress-induced premature senescence dysregulates VEGF and CFH expression in retinal pigment epithelial cells: implications for age-related macular degeneration
Genetic analysis of tissue glutathione concentrations and redox balance
Although ligand-receptor pathways are often thought of as linear paths from engagement to transcription/translation, many studies show that enhanced oxidative potential can augment or suppress signaling pathways, including those related to MUC5AC, while more recently, oxidatively driven epigenetic effects on gene transcription have also been reported (2932)
The hypoglycemic drug SGLT2 inhibitors also shows promising therapeutic effect on diabetes-induced renal tubular damage by restoring autophagy (156)
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