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As do other arsenicals, it induces G 2 /M cell cycle arrest and triggers apoptosis through disruption of mitochondrial functions and JNK activation and is responsible for reactive oxygen species production (Diaz et al., 2008)

Its structure includes two non-standard amino acids aminoisobutyric acid (Aib) and D-2-naphthylalanine (D-2-Nal) which set it apart from naturally occurring peptides

The + 4-oxidation state of Mn in MnO imparts strong oxidative properties, enabling its responsiveness to reducing agents like GSH, allowing it to be rapidly reduced and degraded by GSH

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For readers looking specifically at HPG-axis compounds, our peptides for testosterone guide separates those mechanisms from GH secretagogues