Disclosing Your GLP-1 Use Always tell any healthcare provider if you are taking semaglutide, whether it is a branded version like Wegovy or a compounded version from a pharmacy
The metabolite thus generated, GLP-1 936 amide or GLP-1 (937), is inactive and may even act as a competitive antagonist at the GLP-1 receptor (44, 153), although its formation does not seem to result in antagonism in vivo (339)
But researchers caution that the study, though large, was not the sort of controlled clinical trial needed to confirm that GLP-1 drugs offer a safe and effective way to treat addiction
Unlike earlier GHRPs (GHRP-2, GHRP-6), ipamorelin is highly selective for GHS-R1a without elevating ACTH, cortisol, prolactin, or aldosterone at therapeutic doses the most common reason it is preferred over non-selective GHRPs
doi:10.1016/S0140-6736(20)32667-2