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However, if you already have a history of migraines, hormonal or metabolic changes from the medication could act as a trigger

NICE guidance emphasises individualised glycaemic targets, particularly when multiple medications affecting glucose metabolism are used concurrently

However, if you are already established on metformin and your GI system has adapted, adding low-dose tirzepatide (2.5 mg) typically produces manageable symptoms

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Prescription drugs : Off-label use of medications like acarbose to optimize blood sugar control