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FDA-approved chronic weight-management medications such as Wegovy and Zepbound are intended to be used alongside reduced-calorie eating and increased physical activity

doi: 10.1073/pnas.0901043106 67 YuCXLiSWhortonAR

Research suggests that intramuscular delivery achieves significantly higher plasma concentrations than oral supplementation, making injectable Vitamin C a clinically effective option for patients with deficiency, compromised immune function, or chronic fatigue

In the SURMOUNT-1 trial, approximately 9% of participants on the highest 15mg dose did not achieve clinically meaningful weight loss of 5% or more

These findings are from peer-reviewed research and represent the current best evidence on GLP-1 medications and bone