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This longer half-life is beneficial for bodybuilders and athletes as it gives time to bind to receptors and exert hormonal effects

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However, emerging research also links gut barrier dysfunction to systemic conditions including autoimmune diseases, body syndrome, obesity, type 2 diabetes, non-alcoholic fatty liver disease, heart disease, and even neurological and psychiatric conditions through the gut-brain axis

doi: 10.1016/j.ctim.2019.102273