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Tandon says many doctors are considering semaglutide a breakthrough treatment

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Berberine studies suggest more modest effects, though direct head-to-head comparisons are lacking

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Symptomatic hypoglycemia was not different between lixisenatide and placebo (15.3% vs

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There's good support for patience here: time to therapeutic effect remains similar at roughly 8 to 12 weeks regardless of escalation speed, so patients don't sacrifice their treatment timeline by following gradual protocols

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