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Additionally, lipid metabolic products, such as oxidized cholesterol derivatives, can activate inflammatory pathways and damage vascular endothelium (46)

This is medically appropriate (the FDA doesn't require lifestyle intervention failure, only insurance does) but means paying out-of-pocket rather than using insurance

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PubMed Sanyal AJ, et al

First, the trials are not head-to-head

Studies show Epithalon enhances expression of antioxidant response element (ARE)-regulated genes, leading to increased synthesis of protective proteins and enzymes