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The first experiment asked whether a dual GLP-1/GIP agonist (tirzepatide, the active ingredient in Mounjaro) causes outsized muscle loss in obese mice

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However, case reports pointed to more serious outcomes like systemic toxicity, infections from injections, and even possible links to melanoma

This interaction serves to stimulate their migratory activity and cytokine production, thereby exacerbating psoriatic dermatitis (54)

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febbraio 2019;236(2):60311