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No completed human efficacy or safety trial

The thigh is the most common location for intramuscular self-injections

We do not prescribe it to every patient who requests it

It is more aligned with bringing the body into a state where weight-loss strategies can work as intended

IM B12 injection is especially appropriate when oral supplementation has been inadequate, when absorption is compromised, or when neurological symptoms are present (Stabler, New England Journal of Medicine , 2013)