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If you do inject insulin into your muscles, it'll be used up much more quickly and potentially cause bruising
a digital twin) and uncover subtle, complex patterns (like, for example, how a specific sleep pattern interacts with a genetic marker to influence the GLP-1's effect)
This cascade of oxidative stress can lead to cellular dysfunction and damage, significantly impacting various tissues and organs [174, 175]
You mentioned gut, and I think its probably worth noting that, you know, the largest concentration of diamine oxidase is in the lining of the gut, meaning if you have any digestive issues, gastrointestinal inflammation, you immediately lose that, you know, frontline histamine-metabolizing layer, which also then leaves you more vulnerable to reactions to dietary histamines, because its DAO that would normally take care of those for you
Safety and tolerability of sitagliptin in clinical studies: a pooled analysis of data from 10,246 patients with type 2 diabetes
doi: 10.1073/PNAS.092672899 52 Garca-SezAJ
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