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Contraindications remain somewhat speculative given limited human data

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10.1182/blood-2013-01-480129 193 Nayak-KapoorA.HaoZ.SadekR.DobbinsR.MarshallL.VahanianN

A few examples of the activities played by GSTs on antineoplastic agents and their contribution to drug resistance in cancer are the following: Cisplatin Platinum chemotherapeutic drugs are among the most extensively used anticancer agents 73

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Mechanistic studies examine its interactions with nitric oxide signaling, prostaglandin pathways, and gastrointestinal dopamine and serotonin turnover, including their relevance to experimental models of intestinal inflammation and gastrointestinal dysfunction