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This medication is given via subcutaneous injection (fine needle into the fatty tissue of the abdomen), once per week
Curiously, inhibition of ryanodine receptors (Ryr) provides a protective effect in situations of intracellular calcium dyshomeostasis (Huang et al., 2017) and could be identified as a potential self-protective mechanism against increases in free intracellular calcium, although its loss also affects synaptic plasticity by impairing remodeling of dendritic spines and decreasing excitatory synapses (Bertan et al., 2020)
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Nonetheless, even the perfect non-invasive treatment may lead to some bruising, necessitating plans for post-procedural and post-operative care
Patients are advised to maintain balanced diets and regular physical activity for best results
Garzilli, I
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