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These patterns suggest an acute infection or another condition that has emerged independently of semaglutide therapy and requires clinical diagnosis and care

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An alternative interpretation for the first phase could be a rapid noncovalent interaction between PfGrx and GSSG in the vicinity of roGFP2, however, this seems less likely considering the smaller values for the structurally similar PfGrx mutants or, in particular, the rxYFP fusion constructs with ScGrx1 (Table 1)

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wherein TFA, PhSMe, PhOMe, EDT, H 2 O, TIS and PhOH are in a volume ratio of 80-90:0-5:0-3:0-5:0-5:0-2:0-5, with TFA:PhSMe:PhOH:EDT:H 2 O = 85:5:3:5:2 being preferred