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Taken together, these results indicate that modulation of direct GLP-1R-cholesterol interactions is a valid strategy to fine-tune beta cell incretin receptor responses, providing a new avenue for further investigation of novel ways to improve GLP-1R signalling outputs
1 Introduction Parkinsons disease (PD) is a neurodegenerative condition associated with progressive neuronal loss in the substantia nigra pars compacta (SNpc), the major origin of dopamine release in the brain (Ramesh and Arachchige, 2023)
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