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Moreover, these drugs are often associated with side effects such as gastrointestinal distress, dizziness, and nausea, further limiting their long-term clinical utility ( 4.4 Socioeconomic burden and the need for cost-effective therapies Beyond its medical impact, AD imposes a substantial socioeconomic burden, affecting patients, caregivers, and healthcare systems
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It is important to note that many of the studies examining the efficacy of lipoic acid for the treatment of diabetic neuropathy have been conducted by one German research group and funded by the manufacturer of lipoic acid in Germany
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