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Above all, as with all MR studies, pleiotropy effects in the MR setting are challenging ( 5 Conclusion In conclusion, we provided evidence that genetically proxied GLP-1RAs were associated with a reduced risk of ED, and to a lesser extent, T2D, obesity, hypertension and CVD mediated this effect
This is because the enzyme is working too fast in its conversion
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Meal timing and composition play crucial roles in optimising incretin response
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