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While weight loss might be minimal at this stage, some users report shedding 2-4 pounds

Current research gaps and future directions Despite encouraging results, important questions remain

As a result of this evidence, the BNF (British National Formulary) has listed warfarin and Tamoxifen as having a severe interaction due to the increased risk of bleeding 59

There is, however, some concern that GLP-1 RAs may affect the absorption of immunosuppressive drugs owing to their role in slowing gastric emptying.4,5 To date, data on tacrolimus doses and levels have been published on a small number of KT recipients treated with GLP-1 RAs.6,811 In our study, with a significant number of subjects, trough levels, doses and tacrolimus C/D ratio did not change significantly during follow-up, allowing confidence regarding the safety of immunosuppressive treatment

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