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Similar phenotypes were also observed when GCLC was deleted in HCC-1806 cells (a human breast cancer cell line), which showed complete depletion of GSH levels (Fig
For cocaine use disorder, an ongoing clinical trial is registered (NCT07227948), and there is also an ongoing trial for methamphetamine use disorder (NCT07204249)
Unexpectedly, we also observed telomere length increase in two telomerase-positive cancer cell lines however, this was found to occur through ALT activation
Overdose or chronic high-dose use without adequate glutathione recovery causes this risk
& Patel, U
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