Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice
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Preclinical data across animal and in vitro models consistently points to roles in intestinal lining integrity, inflammation modulation, and mucosal tissue repair
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However, even lower BAC levels can lead to impaired cognitive and motor functions, affecting judgment, coordination, and reaction time