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The intracellular signaling pathways induced upon RAGE activation depend on the ligands that bind to it and the on the cell type where it is expressed

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One compound of research interest is the human peptide GHK (glycyl-L-histidyl-L-lysine), a copper-binding peptide known for its diverse biological actions that have been studied in the context of aging-related diseases and conditions

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The angiotensin AT4 receptor subtype as a target for the treatment of memory dysfunction associated with Alzheimer's disease

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