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At these concentrations, the GLP-1 receptor activation is sufficient to engage anti-inflammatory pathways without triggering the gastrointestinal side effects that make full-dose therapy difficult for many patients

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J Steroid Biochem 20:121128 Gulino A, Screpanti I, Pasqualini JR (1984) Differential estrogen and antiestrogen responsiveness of the uterus during development in the fetal, neonatal and immature guinea pig