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Using mice, human serum, and in vitro experiments, we analyzed the effect of short-term larazotide, a zonulin antagonist, treatment during preclinical phases of arthritis to show the existence of the gutjoint axis and open therapeutic opportunities to prevent arthritis

Abstract Glioma is the most common intracranial malignant tumor in adults and the 5-year survival rate of glioma patients is extremely poor, even in patients who received Stupp treatment after diagnosis and this forces us to explore more efficient clinical strategies

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Unique attributes of orbital fibroblasts and global alterations in IGF-1 receptor signaling could explain thyroid-associated ophthalmopathy

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However, reports of rare adverse events, including the development of autoimmune disorders such as GD following vaccination, have raised concerns