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Real-world results vary based on dose, lifestyle, baseline weight, and adherence

J.et al (2025)

The following table summarizes common claims and their evidence basis: The key pattern: most benefits are real only for individuals who are actually deficient in B12

Willow , for example, ran ads encouraging patients to cancel their gym membership and promised rapid weight lossmessaging that directly contradicts clinical guidelines and feeds into unhealthy narratives (they also prescribe to patients regardless of BMI)

Its also important to discuss any history of diabetic retinopathy (an eye problem) or mental health conditions like depression

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