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Vitamin B9 (Folate/Folic Acid) : Critical for DNA synthesis, cell division, and the formation of red blood cells

NNMT consumes S-adenosylmethionine (SAM) as a methyl donor, and inhibiting NNMT could theoretically increase SAM availability for other methylation reactions

Let's take a closer look at each option, as they each have their own advantages and considerations

It also increases the available amount of SAMe (S- adenosylmethionine), which acts as a mood enhancer and works as an effective alternative to tricyclic antidepressant [4]

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Hydroxocobalamin, which the body retains longer than cyanocobalamin, often allows less frequent dosing once levels stabilize