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2019;316:E88094
T.GuoA.KlessigD
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Rare but serious potential complications include pancreatitis, gallbladder problems, and a theoretical risk of thyroid tumors based on animal studies
The included studies on exendin-4 exposure were all performed in mouse models ( In rat, mouse and rabbit models without systemic inflammation, the other GLP1-receptor agonists (except exendin-4), dose dependently caused reduced fetal weight and/or growth, retardation of ossification, irregular ossification, and/or skeletal variants such as wavy ribs ( Table 1 )
Restart the Medication or Another Therapy Restarting a GLP-1 or another older medication or metabolic or bariatric surgery are effective ways to prevent putting back on the pounds
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